Protection against severe infectious disease in the past
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DOI: 10.1080/20477724.2021.1878443
Abstract: ABSTRACT Before the 20th century many deaths in England, and most likely a majority, were caused by infectious diseases. The focus here is on the biggest killers, plague, typhus, smallpox, tuberculosis, cholera, typhoid, dysentery, childhood… read more here.
Keywords: infectious disease; disease past; infectious diseases; severe infectious ... See more keywords
Impact of Sickle Cell Trait Hemoglobin on the Intraerythrocytic Transcriptional Program of Plasmodium falciparum
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DOI: 10.1128/msphere.00755-21
Abstract: Sickle-trait hemoglobin (HbAS) confers nearly complete protection from severe, life-threatening malaria, yet the molecular mechanisms that underlie HbAS protection from severe malaria remain incompletely understood. Here, we used transcriptome sequencing (RNA-seq) to measure the impact… read more here.
Keywords: protection; protection severe; plasmodium falciparum; trait hemoglobin ... See more keywords