Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.111976
Abstract: A series of vincamine derivatives were designed, synthesized and evaluated as pancreatic β-cells protective agents for type 2 diabetes mellitus. Most of the compounds displayed potent pancreatic β-cells protective activities and five derivatives were found… read more here.
Keywords: protective agents; type diabetes; diabetes mellitus; pancreatic cells ... See more keywords
On-Demand Release of Protective Agents Triggered by Environmental Stimuli
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.00304
Abstract: The aim of this study was to develop smart materials with stimuli-responsive properties for the long-term protection of steel. The idea was to obtain a tailored and controlled release of protective agents in response to… read more here.
Keywords: protective agents; demand release; agents triggered; release protective ... See more keywords
Editorial: Nature Inspired Protective Agents Against Oxidative Stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.859549
Abstract: Oxidative stress is the result of an imbalance between pro-oxidant and antioxidant species at cellular level, also defined as a lack in redox signaling and control. Despite small amounts of reactive oxygen or nitrogen species… read more here.
Keywords: stress; agents oxidative; nature inspired; oxidative stress ... See more keywords
Marine Algal Polyphenols as Skin Protective Agents: Current Status and Future Prospectives
Sign Up to like & getrecommendations! Published in 2023 at "Marine Drugs"
DOI: 10.3390/md21050285
Abstract: The skin is the outermost anatomical barrier, which plays a vital role in the maintenance of internal homeostasis and protection against physical, chemical, and biological detractors. Direct contact with various stimuli leads to several physiological… read more here.
Keywords: protective agents; polyphenols skin; algal polyphenols; marine algal ... See more keywords
Natural Reno-Protective Agents against Cyclosporine A-Induced Nephrotoxicity: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227771
Abstract: CA (cyclosporine A) is a powerful immunosuppressing agent that is commonly utilized for treating various autoimmune illnesses and in transplantation surgery. However, its usage has been significantly restricted because of its unwanted effects, including nephrotoxicity.… read more here.
Keywords: protective agents; natural reno; reno protective; agents cyclosporine ... See more keywords