Protective effects of resveratrol on the ethanol‐induced disruption of retinogenesis in pluripotent stem cell‐derived organoids
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13601
Abstract: Prenatal alcohol exposure‐induced fetal alcohol syndrome (FAS) can lead to serious maldevelopment in many organ systems, including the eyes. In the present study, the effects of alcohol exposure on early development of the human retina… read more here.
Keywords: protective effects; effects resveratrol; ethanol induced; resveratrol ethanol ... See more keywords
Protective Effects of Lovastatin in a Population‐Based ALS Study and Mouse Model
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26600
Abstract: The objective of this study was to use a novel combined pharmacoepidemiologic and amyotrophic lateral sclerosis (ALS) mouse model approach to identify potential motor neuron protective medications. read more here.
Keywords: protective effects; effects lovastatin; based als; population based ... See more keywords
Apremilast exerts protective effects on stroke outcomes and blood–brain barrier (BBB) dysfunction through regulating Rho‐associated protein kinase 2 expression
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2677
Abstract: Stroke is a devastating event and a huge public health concern worldwide. Apremilast (APR) is a selective inhibitor of phosphodiesterase‐4 involved in various neurological diseases, including stroke. However, the protective effects of APR on stroke… read more here.
Keywords: protective effects; blood brain; brain barrier; brain ... See more keywords
Itaconate Has Limited Protective Effects in Experimental Malaria Models
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DOI: 10.1002/eji.202451595
Abstract: In severe malaria, dysregulated metabolism and excessive inflammatory responses contribute to fatal outcomes. Therapeutic strategies that address both metabolic and inflammatory balances are thus required. Itaconate, a metabolite produced by aconitate decarboxylase 1 (ACOD1), is… read more here.
Keywords: limited protective; protective effects; itaconate limited; malaria ... See more keywords
Protective Effects of Atorvastatin on LPS‐Induced Testicular Damage: Modulation of Spermatogenesis via PPAR‐γ, NF‐κB, and NLRP3 Pathways
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4851
Abstract: Male infertility represents a considerable global health issue, frequently linked to oxidative stress and inflammation‐related dysfunction of the testes. Atorvastatin (ATV), a commonly prescribed statin, has effects that extend beyond merely lowering lipid levels. Recent… read more here.
Keywords: ppar; protective effects; induced testicular; testicular damage ... See more keywords
The protective effects of propofol against renal ischemia-reperfusion injury are potentiated by norisoboldine treatment via inhibition of oxidative stress pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22937
Abstract: Acute kidney injury (AKI) is a significant worldwide health problem. The protective effects of norisoboldine (NOR) against ischemia/reperfusion (I/R) induced renal injury in a rat model were evaluated. AKI was induced in rats by I/R.… read more here.
Keywords: treatment; ischemia reperfusion; injury; protective effects ... See more keywords
The protective effects of thymol and carvacrol against di (2‐ethylhexyl) phthalate‐induced cytotoxicity in HEK‐293 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23092
Abstract: The protective effects of thymol and carvacrol, two phenolic monoterpenes with a wide spectrum of pharmacological effects, against the oxidative stress produced by the di (2‐ethylhexyl) phthalate (DEHP) in human embryonic kidney cells 293 cells… read more here.
Keywords: protective effects; 293 cells; thymol carvacrol; hek 293 ... See more keywords
The protective effects of esculetin against Doxorubicin‐Induced hepatotoxicity in rats: Insights into the modulation of Caspase, FOXOs, and heat shock protein pathways
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23861
Abstract: Doxorubicin (DOX) is an anthracycline antibiotic widely employed to treat carcinoma. Nevertheless, severe cardiotoxic side effects restrict its clinical use. Esculetin, a natural flavonoid, is found abundantly in plants. This study evaluated the protective effects… read more here.
Keywords: dox esculetin; dox; induced hepatotoxicity; protective effects ... See more keywords
The Protective Effects of Saxagliptin and Cilostazol in an Experimental Model of Cyclophosphamide‐Induced Nephrotoxicity in Rats: Targeting iNOS/NF‐kB and Nrf‐2/HO‐1 Pathways
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70196
Abstract: Cyclophosphamide (CYP) is an extensively used immunosuppressive drug and chemotherapeutic agent for various malignancies. Nevertheless, its use is limited due to adverse effects, including nephrotoxicity. Saxagliptin is a DPP4 inhibitor, while cilostazol serves as an… read more here.
Keywords: saxagliptin cilostazol; protective effects; nephrotoxicity induced; group ... See more keywords
Morphological evidence of the protective effects of a synthetic chalcone against the striatal myelin damage induced by glutaric acid
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Developmental Neuroscience"
DOI: 10.1002/jdn.10256
Abstract: Ultrastructural features of striatal white matter and cells in an in vivo model of glutaric acidemia type I created by intracerebral injection of glutaric acid (GA) were analyzed by transmission electron microscopy and immunohistochemistry. To… read more here.
Keywords: protective effects; morphological evidence; damage; glutaric acid ... See more keywords
Identification of a novel probiotic and its protective effects on NAFLD via modulating gut microbial community.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11820
Abstract: BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is becoming the most common progressive liver diseases. Therapeutic strategy based on gut-liver axis and probiotics is a promising approach for the treatment of NAFLD. However, rare probiotics have… read more here.
Keywords: liver; protective effects; effects nafld; novel probiotic ... See more keywords