Protective efficacy of nafronyl in diabetic retinopathy through targeted inhibition of key enzymes
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2625
Abstract: Diabetic retinopathy is governed by abnormal apoptosis, increased capillary pressure, and other linked pathology that needs an efficient treatment by multitargeted approaches. Thus, the current study aimed to explore the potential of inhibition of targeted… read more here.
Keywords: protective efficacy; efficacy nafronyl; inhibition; diabetic retinopathy ... See more keywords
Protective Efficacy of Yogurt, Milk, and Fluoridated Tooth Creme Against Acidic Beverages on Human Teeth: Stereomicroscopic and Ultrastructural Analyses
Sign Up to like & getrecommendations! Published in 2025 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.24819
Abstract: Acidic beverages can cause significant demineralization and erosive ultrastructural changes in human teeth, while milk and yogurt can prevent dental erosion. This in vitro study aimed to quantify and compare the protective efficacy of yogurt… read more here.
Keywords: protective efficacy; human teeth; acidic beverages; yogurt milk ... See more keywords
Key mutations in the spike protein of SARS‐CoV‐2 affecting neutralization resistance and viral internalization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28407
Abstract: To control the ongoing COVID‐19 pandemic, a variety of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccines have been developed. However, the rapid mutations of SARS‐CoV‐2 spike (S) protein may reduce the protective efficacy of… read more here.
Keywords: neutralization; key mutations; protective efficacy; spike protein ... See more keywords
Reducing Viral Inhibition of Host Cellular Apoptosis Strengthens the Immunogenicity and Protective Efficacy of an Attenuated HSV-1 Strain
Sign Up to like & getrecommendations! Published in 2019 at "Virologica Sinica"
DOI: 10.1007/s12250-019-00156-7
Abstract: Herpes simplex virus 1 (HSV-1), a member of α herpesviruses, shows a high infectivity rate of 30%–60% in populations of various ages. Some herpes simplex (HSV) vaccine candidates evaluated during the past 20 years have… read more here.
Keywords: hsv; cellular apoptosis; hsv strain; protective efficacy ... See more keywords
Use Chou's 5-steps rule to evaluate protective efficacy induced by antigenic proteins of Mycobacterium tuberculosis encapsulated in chitosan nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117961
Abstract: The study focuses on whether antigenic proteins encapsulated in biopolymeric nanoparticles can augment protective efficacy. Chitosan nanoparticles (ChN) were prepared by ionic gelation method and Culture Filtrate Proteins (CFP) - CFP-10 and CFP-21 of Mycobacterium… read more here.
Keywords: chn cfp; antigenic proteins; cfp; protective efficacy ... See more keywords
Evaluation of the protective efficacy of recombinant protective antigen vaccine (GC1109)-immunized human sera using passive immunization in a mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.12.048
Abstract: The protective efficacy of human sera from vaccinated individuals with a new recombinant protective antigen anthrax vaccine (GC1109) against lethal spore challenge was evaluated in a mouse model. Eighteen human sera were selected from the… read more here.
Keywords: gc1109; protective efficacy; human sera; vaccine ... See more keywords
Protective efficacy of peptides from Plasmodium vivax circumsporozoite protein
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.03.063
Abstract: Highlights • Short repeat-region peptides from PvCSP on a VLP protect against malaria.• The AGDR tetramer from PvCSP VK210 can, on a VLP, also protect against malaria.• Full-length PvCSP is much less protective as a… read more here.
Keywords: circumsporozoite protein; peptides plasmodium; protective efficacy; efficacy peptides ... See more keywords
Immunogenicity and protective efficacy of inactivated equine influenza (H3N8) virus vaccine in murine model.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2017.08.013
Abstract: Equine influenza viruses (EIVs) are responsible for acute contagious respiratory infection in equines and the disease remains a major threat for equine population throughout the world despite vaccination strategies in place. The present study was… read more here.
Keywords: protective efficacy; model; h3n8 virus; vaccine ... See more keywords
Protective Efficacy of Candidate Vaccines Prior to Human Clinical Trials.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2018.08.005
Abstract: Immunization of animals is one of the key standards for evaluation of vaccine efficacy prior to human clinical trials. However, vaccine organizations should not over-interpret these results as protective efficacy in animals may not be… read more here.
Keywords: prior human; efficacy candidate; human clinical; protective efficacy ... See more keywords
Cutting-edge progress in the protective efficacy of nanovaccines against poultry diseases
Sign Up to like & getrecommendations! Published in 2025 at "World's Poultry Science Journal"
DOI: 10.1080/00439339.2025.2461723
Abstract: SUMMARY Pathogens reduce poultry production worldwide by millions of tons and millions of dollars annually. To fence this problem, nanovaccine R&D has entered as an alternative to prevent infectious diseases. Nanovaccines can act as nanocarriers… read more here.
Keywords: protective efficacy; poultry diseases; cutting edge; nanovaccines poultry ... See more keywords
Protective efficacy of Helianthemum lippii–derived silver nanoparticles against CdCl₂-induced oxidative, endocrine, and reproductive toxicity
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Food Properties"
DOI: 10.1080/10942912.2025.2580742
Abstract: ABSTRACT Cadmium chloride (CdCl₂), a widespread environmental contaminant, poses serious risks to food safety and human health by disrupting endocrine balance, impairing hematological parameters, and damaging reproductive organs. This study assessed the protective efficacy of… read more here.
Keywords: protective efficacy; cdcl induced; lippii derived; helianthemum lippii ... See more keywords