Adjuvants: Engineering Protective Immune Responses in Human and Veterinary Vaccines.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1892-9_9
Abstract: Adjuvants are key components of many vaccines, used to enhance the level and breadth of the immune response to a target antigen, thereby enhancing protection from the associated disease. In recent years, advances in our… read more here.
Keywords: responses human; human veterinary; engineering protective; adjuvants engineering ... See more keywords
Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C. muridarum challenge.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.03.070
Abstract: OBJECTIVES To test vaccines, formulated with novel antigens, to protect mice against Chlamydia infections. METHODS To determine the ability of polymorphic membrane proteins (Pmps) to induce cross-species protective immune responses, recombinant fragments from all nine… read more here.
Keywords: membrane proteins; immune responses; polymorphic membrane; ability ... See more keywords
Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08590-x
Abstract: The protozoan parasite Giardia is a highly prevalent intestinal pathogen with a wide host range. Data obtained in mice, cattle and humans revealed the importance of IL-17A in the development of a protective immune response… read more here.
Keywords: response; response giardia; giardia; immune response ... See more keywords
A temperature sensitive Mycobacterium paragordonae induces enhanced protective immune responses against mycobacterial infections in the mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15458-7
Abstract: Recently, we introduced a temperature sensitive Mycobacterium spp., Mycobacterium paragordonae (Mpg). Here, we checked its potential as a candidate for live vaccination against Mycobacterium tuberculosis and Mycobacterium abscessus. Intravenous infections of mice with Mpg led… read more here.
Keywords: temperature sensitive; immune responses; mycobacterium; protective immune ... See more keywords
Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response
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DOI: 10.1128/jvi.00523-22
Abstract: Hepatitis C virus (HCV) E2-CD81 binding dampens protective immune response. We have identified that an alteration of amino acids in the front layer of soluble E2 (sE2) disrupts CD81 interaction and alters the cytokine response.… read more here.
Keywords: protective immune; cd81 binding; hcv; hepatitis virus ... See more keywords
S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008119
Abstract: Neutrophils are essentially involved in protective immune responses against invading infective larvae of filarial nematodes. The present study investigated the impact of S100A8/S100A9 on protective immune responses against the rodent filarial nematode Litomosoides sigmodontis. S100A9… read more here.
Keywords: s100a8 mice; responses invading; immune responses; protective immune ... See more keywords
Radiation-Inactivated S. gallinarum Vaccine Provides a High Protective Immune Response by Activating Both Humoral and Cellular Immunity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.717556
Abstract: Salmonella enterica subsp. enterica serovar Gallinarum (SG) is a common pathogen in chickens, and causes an acute systemic disease that leads to high mortality. The live attenuated vaccine 9R is able to successfully protect chickens… read more here.
Keywords: response; protective immune; immune response; vaccine ... See more keywords
THαβ Immunological Pathway as Protective Immune Response against Prion Diseases: An Insight for Prion Infection Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14020408
Abstract: Prion diseases, including Creutzfeldt–Jakob disease, are mediated by transmissible proteinaceous pathogens. Pathological changes indicative of neuro-degeneration have been observed in the brains of affected patients. Simultaneously, microglial activation, along with the upregulation of pro-inflammatory cytokines,… read more here.
Keywords: immunological pathway; pathway protective; prion; prion diseases ... See more keywords