C3a receptor antagonist therapy is protective with or without thrombolysis in murine thromboembolic stroke
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DOI: 10.1111/bph.14989
Abstract: Intravenous thrombolysis (IVT) after stroke enhances C3a generation, which may abrogate the benefits of reperfusion. The C3aR antagonist SB290157 is neuroprotective following transient but not permanent middle cerebral artery occlusion (MCAo). SB290157 remains untested in… read more here.
Keywords: receptor antagonist; c3a receptor; therapy protective; thrombolysis ... See more keywords