ALDOA protects cardiomyocytes against H/R-induced apoptosis and oxidative stress by regulating the VEGF/Notch 1/Jagged 1 pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-020-03943-z
Abstract: Myocardial infarction (MI) is a myocardial necrosis disease caused by continuous ischemia and hypoxia. Abnormal expression of aldolase A (ALDOA) has been reported in cardiac hypertrophy, heart failure and other cardio-cerebrovascular diseases. The present study… read more here.
Keywords: cardiomyocytes induced; notch jagged; stress; aldoa protects ... See more keywords
Quercetin protects cardiomyocytes against doxorubicin-induced toxicity by suppressing oxidative stress and improving mitochondrial function via 14-3-3γ
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2018.1564948
Abstract: Abstract Cardiotoxicity limits the clinical applications of doxorubicin (Dox), which mechanism might be excess generation of intracellular ROS. Quercetin (Que) is a flavonoid that possesses anti-oxidative activities, exerts myocardial protection. We hypothesized that the cardioprotection… read more here.
Keywords: stress improving; induced toxicity; improving mitochondrial; suppressing oxidative ... See more keywords
Capsaicin protects cardiomyocytes against lipopolysaccharide-induced damage via 14-3-3γ-mediated autophagy augmentation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.659015
Abstract: Background: The myocardium is susceptible to lipopolysaccharide (LPS)-induced damage in sepsis, and cardiac dysfunction is a leading cause of mortality in patients with sepsis. The changes in cardiomyocyte autophagy in sepsis and the effects and… read more here.
Keywords: lps induced; induced damage; damage; capsaicin protects ... See more keywords