Aesculin protects against DSS-Induced colitis though activating PPARγ and inhibiting NF-кB pathway.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172453
Abstract: Aesculin, a natural product from the traditional and widely-used Chinese medicine named Cortex fraxini, has attracted attention as a novel therapeutic modulator of inflammation. However, little is known about its effect on ulcerative colitis (UC).… read more here.
Keywords: protects dss; dss induced; colitis; ulcerative colitis ... See more keywords
PAM3 protects against DSS-induced colitis by altering the M2:M1 ratio
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-63143-z
Abstract: Inflammation of the gastrointestinal tract contributes to the development of inflammatory bowel disease (IBD). Human IBD is modeled by administering dextran sulfate sodium (DSS) to mice. In humans and mice, inflammatory M1 macrophages contribute to… read more here.
Keywords: pam3 protects; protects dss; dss induced; colitis ... See more keywords