R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin.
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DOI: 10.1016/j.bbrc.2018.03.126
Abstract: BACKGROUND & AIMS Leucine-rich repeat G-protein-coupled receptor 4 (LGR4) and its ligands R-spondin1-4 (Rspos) have been vastly investigated in embryonic development. The biological functions of Rspos-LGR4 system in liver remains largely unknown. Here, we explored… read more here.
Keywords: lgr4; hypoxia reoxygenation; protects hepatocytes; dmog induced ... See more keywords