JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson's disease: mitochondrial protection and antioxidant properties.
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2020.11.005
Abstract: We have previously shown that JM-20, a new chemical entity consisting of 1,5-benzodiazepine fused to a dihydropyridine moiety, protects against rotenone-induced neurotoxicity in an experimental model of Parkinson's disease (PD). The aim of this study… read more here.
Keywords: protection; protects hydroxydopamine; induced neurotoxicity; ohda ... See more keywords
The 1-Tosylpentan-3-one Protects against 6-Hydroxydopamine-Induced Neurotoxicity
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18051096
Abstract: Previous studies have demonstrated that the marine compound austrasulfone, isolated from the soft coral Cladiella australis, exerts a neuroprotective effect. The intermediate product in the synthesis of austrasulfone, dihydroaustrasulfone alcohol, attenuates several inflammatory responses. The… read more here.
Keywords: tosylpentan one; ohda induced; protects hydroxydopamine; one protects ... See more keywords