Hepatocellular iNOS protects liver from NASH through Nrf2-dependent activation of HO-1.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.144
Abstract: Multiple molecular events are involved in non-alcoholic steatohepatitis (NASH). There is no consensus on the role of inducible nitric oxide synthase (iNOS) in the progression of NASH. The present study therefore investigated the role of… read more here.
Keywords: protects liver; liver nash; nash nrf2; inos protects ... See more keywords
Thioredoxin-1 promotes macrophage reverse cholesterol transport and protects liver from steatosis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.06.109
Abstract: Atherosclerosis is characterized by the accumulation of excess cholesterol in plaques. Reverse cholesterol transport (RCT) plays a key role in the removal of cholesterol. In the present study, we examined the effect of thioredoxin-1 (Trx-1)… read more here.
Keywords: protects liver; liver steatosis; reverse cholesterol; cholesterol ... See more keywords
Antipsychotic Drug Aripiprazole Protects Liver Cells from Oxidative Stress
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158292
Abstract: Antipsychotics used to treat schizophrenia can cause drug-induced liver injury (DILI), according to the Roussel Uclaf Causality Assessment Method. The role of oxidative stress in triggering injury in these DILI cases is unknown. We repeatedly… read more here.
Keywords: cells oxidative; stress; oxidative stress; liver cells ... See more keywords