Acetoacetate protects macrophages from lactic acidosis-induced mitochondrial dysfunction by metabolic reprograming
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-27426-x
Abstract: Lactic acidosis, the extracellular accumulation of lactate and protons, is a consequence of increased glycolysis triggered by insufficient oxygen supply to tissues. Macrophages are able to differentiate from monocytes under such acidotic conditions, and remain… read more here.
Keywords: acidosis induced; acetoacetate protects; protects macrophages; metabolic ... See more keywords
Phloretin protects macrophages from E. coli-induced inflammation through the TLR4 signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.1910.10063
Abstract: Macrophages are the cells of the first-line defense system, which protect the body from foreign invaders such as bacteria. However, Gram-negative bacteria have always been the major challenge for macrophages due to the presence of… read more here.
Keywords: phloretin; macrophages coli; coli; signaling pathway ... See more keywords