Prior transient exposure to interleukin-21 delivered by recombinant adeno-associated virus vector protects mice from hepatitis B virus persistence.
Sign Up to like & getrecommendations! Published in 2021 at "Antiviral research"
DOI: 10.1016/j.antiviral.2021.105076
Abstract: Chronic infection of hepatitis B virus (HBV) is a high risk factor for hepatic diseases, such as liver fibrosis, cirrhosis and hepatocellular carcinoma. Non-responders and hyporesponders to HBV vaccine are not protected from HBV infection.… read more here.
Keywords: protects mice; hbv; recombinant adeno; hepatitis virus ... See more keywords
WITHDRAWN: JIP3 deficiency protects mice from high fat diet-induced liver injury.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.109
Abstract: This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal. read more here.
Keywords: deficiency protects; jip3 deficiency; protects mice; mice high ... See more keywords
Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ginseng Research"
DOI: 10.1016/j.jgr.2020.07.005
Abstract: Abstract Background Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate. Ginsenosides Rc has been reported to maintain glucose balance… read more here.
Keywords: fat diet; protects mice; hfd induced; high fat ... See more keywords
A genetically stable Zika virus vaccine candidate protects mice against virus infection and vertical transmission
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DOI: 10.1038/s41541-021-00288-6
Abstract: Although live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two… read more here.
Keywords: protects mice; vaccine; vertical transmission; zikv ... See more keywords
Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14444
Abstract: Acetaminophen‐induced acute liver injury (AILI) is the most frequent cause of acute liver failure in developed countries. Given the significant limitations associated with N‐acetyl cysteine, the only antidote used to treat AILI, the development of… read more here.
Keywords: liver injury; glycycoumarin protects; protects mice; acetaminophen induced ... See more keywords
Pharmacological Inhibition of Inositol Hexakisphosphate Kinase 1 Protects Mice against Obesity-Induced Bone Loss
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11091257
Abstract: Simple Summary Obesity and diabetes have detrimental impacts on skeletal health that result in an increased fracture risk and impaired fracture healing, conditions associated with significant morbidity and mortality and that are costly to treat.… read more here.
Keywords: obesity induced; inhibition; kinase; protects mice ... See more keywords