STAT1 signaling protects self-reactive T cells from control by innate cells during neuroinflammation
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DOI: 10.1172/jci.insight.148222
Abstract: The transcription factor STAT1 plays a critical role in modulating the differentiation of CD4+ T cells producing IL-17 and GM-CSF, which promote the development of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis… read more here.
Keywords: reactive cells; protects self; stat1 signaling; self reactive ... See more keywords