Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Toxicology"
DOI: 10.1007/s00204-017-1970-5
Abstract: Proper subcellular trafficking is essential to prevent protein mislocalization and aggregation. Transport of the peroxisomal enzyme d-amino acid oxidase (DAAO) appears dysregulated by specific pharmaceuticals, e.g., the anti-overactive bladder drug propiverine or a norepinephrine/serotonin reuptake… read more here.
Keywords: protein; accumulation; vivo; understanding renal ... See more keywords
Synthetic cold-inducible promoter enhances recombinant protein accumulation during Agrobacterium-mediated transient expression in Nicotiana excelsior at chilling temperatures
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2336-z
Abstract: ObjectivesTo exploit cold-inducible biochemical processes beneficial for foreign mRNA transcription, translation and storage, as well as protein product stability, during Agrobacterium-mediated transient expression.ResultsThe efficiency of three different 5′-regulatory sequences to achieve transient expression of the… read more here.
Keywords: transient expression; promoter; expression; cold inducible ... See more keywords
YSL3-mediated copper distribution is required for fertility, seed size and protein accumulation in Brachypodium.
Sign Up to like & getrecommendations! Published in 2021 at "Plant physiology"
DOI: 10.1093/plphys/kiab054
Abstract: Addressing the looming global food security crisis requires the development of high-yielding crops. In agricultural soils, deficiency in the micronutrient copper significantly decreases grain yield in wheat (Triticum aestivum), a globally important crop. In cereals,… read more here.
Keywords: seed; brachypodium; copper; size ... See more keywords
p53 protein accumulation predicts malignant progression in Barrett's metaplasia: a prospective study of 275 patients
Sign Up to like & getrecommendations! Published in 2017 at "Histopathology"
DOI: 10.1111/his.13193
Abstract: The purpose of this study was to determine prospectively whether p53 protein accumulation in biopsies of Barrett's metaplasia (BM) is a predictor of malignant progression, without relying on dysplasia grading. read more here.
Keywords: p53 protein; study; barrett metaplasia; malignant progression ... See more keywords
Proteomic Analysis of Pecan (Carya illinoinensis) Nut Development
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DOI: 10.3390/foods12040866
Abstract: Pecan (Carya illinoinensis) nuts are an economically valuable crop native to the United States and Mexico. A proteomic summary from two pecan cultivars at multiple time points was used to compare protein accumulation during pecan… read more here.
Keywords: protein accumulation; development; seed; pecan carya ... See more keywords
Rapid and Robust Multi-Phenotypic Assay System for ALS Using Human iPS Cells with Mutations in Causative Genes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24086987
Abstract: Amyotrophic lateral sclerosis (ALS) is a major life-threatening disease caused by motor neuron degeneration. More effective treatments through drug discovery are urgently needed. Here, we established an effective high-throughput screening system using induced pluripotent stem… read more here.
Keywords: system; rapid robust; protein accumulation; robust multi ... See more keywords