Quantitative Analysis of Protein S-Acylation Site Dynamics Using Site-Specific Acyl-Biotin Exchange (ssABE).
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9232-4_6
Abstract: Protein S-acylation (palmitoylation) is a reversible lipid modification that is increasingly recognized as an important regulator of protein function, including membrane association, trafficking, and subcellular localization. Most proteomic methods to study palmitoylation allow characterization of… read more here.
Keywords: palmitoylation; protein acylation; site; acyl biotin ... See more keywords
Development of an Acrylamide-Based Inhibitor of Protein S-Acylation.
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DOI: 10.1021/acschembio.1c00405
Abstract: Protein S-acylation is a dynamic lipid post-translational modification that can modulate the localization and activity of target proteins. In humans, the installation of the lipid onto target proteins is catalyzed by a family of 23… read more here.
Keywords: protein acylation; dhhc family; inhibitor; acylation ... See more keywords
The molecular era of protein S-acylation: spotlight on structure, mechanisms, and dynamics
Sign Up to like & getrecommendations! Published in 2018 at "Critical Reviews in Biochemistry and Molecular Biology"
DOI: 10.1080/10409238.2018.1488804
Abstract: Abstract S-Acylation (commonly referred to as S-palmitoylation) is a post-translational modification consisting in the covalent attachment of an acyl chain to a cysteine residue of the target protein. The lability of the resulting thioester bond… read more here.
Keywords: protein; protein acylation; acylation; era protein ... See more keywords
Protein S-acyltransferases and acyl protein thioesterases, regulation executors of protein S-acylation in plants
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.956231
Abstract: Protein S-acylation, also known as palmitoylation, is an important lipid post-translational modification of proteins in eukaryotes. S-acylation plays critical roles in a variety of protein functions involved in plant development and responses to abiotic and… read more here.
Keywords: protein acylation; acylation; acyl protein; protein thioesterases ... See more keywords
The Brain Protein Acylation System Responds to Seizures in the Rat Model of PTZ-Induced Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012302
Abstract: Abnormal energy expenditure during seizures and metabolic regulation through post-translational protein acylation suggest acylation as a therapeutic target in epilepsy. Our goal is to characterize an interplay between the brain acylation system components and their… read more here.
Keywords: acylation system; protein acylation; seizures rat; expression ... See more keywords