Immunohistochemical colocalization of G protein alpha subunits and 5‐HT in the rectal gland of the cartilaginous fish Scyliorhinus canicula
Sign Up to like & getrecommendations! Published in 2017 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.22896
Abstract: Serotonin [5‐hydroxytryptamine (5‐HT)] is an important neuromodulator involved in a wide range of physiological functions. The effects of serotonin are mediated by an extended family of receptors coupled to multiple heterotrimeric G‐proteins, associated with cellular… read more here.
Keywords: alpha subunits; rectal gland; scyliorhinus canicula; gland ... See more keywords
GA‐Binding Protein Alpha Is Involved in the Survival of Mouse Embryonic Stem Cells
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DOI: 10.1002/stem.2673
Abstract: Ets‐related transcription factor GA‐binding protein alpha (GABPα), which is encoded by Gabpa, is expressed in a variety of cell types and is involved in cellular functions such as cell cycle regulation, apoptosis, and differentiation. Here,… read more here.
Keywords: embryonic stem; gabpa null; binding protein; stem ... See more keywords
Targeting the cluster of differentiation 47/signal-regulatory protein alpha axis in myeloid malignancies.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in hematology"
DOI: 10.1097/moh.0000000000000691
Abstract: PURPOSE OF REVIEW The antitumor activity of macrophages is regulated by a balance of prophagocytic and antiphagocytic signals. Cluster of differentiation 47 (CD47), the dominant macrophage immune checkpoint ('do not eat me' signal), interacts with… read more here.
Keywords: regulatory protein; myeloid malignancies; myeloid; protein alpha ... See more keywords
Molecular characterization of Staphylococcus argenteus in Myanmar: identification of novel genotypes/clusters in staphylocoagulase, protein A, alpha‐haemolysin and other virulence factors
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.000869
Abstract: Purpose. Staphylococcus argenteus is a novel emerging species of coagulase‐positive staphylococcus that is genetically closely related to Staphylococcus aureus. To elucidate the molecular differences in the virulence factors (staphylocoagulase, protein A, alpha‐haemolysin, enterotoxin‐like toxin and… read more here.
Keywords: staphylococcus; haemolysin; virulence factors; staphylocoagulase protein ... See more keywords
Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways
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DOI: 10.1371/journal.ppat.1009662
Abstract: Signal-regulatory protein alpha (SIRPA) is a well-known inhibitor of phagocytosis when it complexes with CD47 expressed on target cells. Here we show that SIRPA decreased in vitro infection by a number of pathogenic viruses, including… read more here.
Keywords: anti viral; signal regulatory; regulatory protein; sirpa ... See more keywords
1783-P: Translocon-Associated Protein Alpha (TRAPα) Is Required for Insulin Biosynthesis in ß Cells
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes"
DOI: 10.2337/db19-1783-p
Abstract: The discovery of missense mutations in the signal peptide of preproinsulin that causes congenital diabetes highlights the critical role of ER translocation in insulin biosynthesis. However, the mechanisms that govern these early events in insulin… read more here.
Keywords: protein alpha; insulin biosynthesis; trap; translocon associated ... See more keywords
Fibroblast Activation Protein-Alpha is a Prognostic Biomarker Associated With Ferroptosis in Stomach Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.859999
Abstract: Background: The potential role of fibroblast activation protein-alpha (FAP) in modulating the progression and invasion of stomach adenocarcinoma (STAD) has not yet been comprehensively investigated. This study aimed to explore the role of FAP in… read more here.
Keywords: activation protein; biomarker; fap; fibroblast activation ... See more keywords