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Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202105932
Abstract: Profiling protein expression at single‐cell resolution is essential for fundamental biological research (such as cell differentiation and tumor microenvironmental examination) and clinical precision medicine where only a limited number of primary cells are permitted. With…
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Keywords:
cell protein;
cell;
single cell;
protein analysis ... See more keywords
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Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12277
Abstract: Abstract Small extracellular vesicles (sEVs) have in recent years evolved as a source of biomarkers for disease diagnosis and therapeutic follow up. sEV samples derived from multicellular organisms exhibit a high heterogeneous repertoire of vesicles…
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Keywords:
droplet barcode;
extracellular vesicles;
protein analysis;
barcode sequencing ... See more keywords
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Published in 2024 at "Small Methods"
DOI: 10.1002/smtd.202400375
Abstract: Proteins as crucial components of cells are responsible for the majority of cellular processes. Sensitive and efficient protein detection enables a more accurate and comprehensive investigation of cellular phenotypes and life activities. Here, a protein…
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Keywords:
single cell;
digital microfluidics;
protein analysis;
protein ... See more keywords
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Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.08.043
Abstract: A novel all-in-one paper-based sampling concept for mass spectrometric bottom-up protein analysis is here demonstrated in a chip format integrating instant immunocapture, protein reduction, - alkylation and tryptic digestion all in-device. Conventional laboratory grade filter…
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Keywords:
one paper;
paper;
based sampling;
protein analysis ... See more keywords
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Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.10.108
Abstract: A protein analysis in the pulp of Moro blood oranges (Citrus sinensis L. Osbeck) at the onset and after 30 days of storage at either 4 or 9 °C was performed. All differential proteins belonged to different…
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Keywords:
storage;
moro blood;
pulp;
protein analysis ... See more keywords
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Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c01237
Abstract: Developing miniaturized and rapid protein analytical platforms is urgently needed for on-site protein analysis, which is important for disease diagnosis and monitoring. Liquid marbles (LMs), a kind of particle-coated droplets, as ideal micro-reactors have been…
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Keywords:
plasticine integrated;
liquid plasticine;
analysis;
protein analysis ... See more keywords
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Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c04112
Abstract: Increasing evidence has demonstrated that cells are individually heterogeneous. Advancing the technologies for single-cell analysis will improve our ability to characterize cells, study cell biology, design and screen drugs, and aid cancer diagnosis and treatment.…
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Keywords:
single cell;
analysis;
protein analysis;
approach ... See more keywords
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Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00276
Abstract: The need for high-throughput intact protein analysis has been rising as drug discovery increasingly requires the analysis of large sets of covalent modifiers and protein therapeutics. Liquid chromatography-mass spectrometry (LC-MS) is the primary analytical tool…
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Keywords:
throughput intact;
intact protein;
mass spectrometry;
protein analysis ... See more keywords
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Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae328
Abstract: Abstract The PSIRED Workbench is a long established and popular bioinformatics web service offering a wide range of machine learning based analyses for characterizing protein structure and function. In this paper we provide an update…
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Keywords:
deep learning;
protein analysis;
workbench;
learning psipred ... See more keywords
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Published in 2025 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2024.1507460
Abstract: Single-cell protein analysis has emerged as a powerful tool for understanding cellular heterogeneity and deciphering the complex mechanisms governing cellular function and fate. This review provides a comprehensive examination of the latest methodologies, including sophisticated…
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Keywords:
single cell;
protein analysis;
cell protein;
protein ... See more keywords
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Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12234236
Abstract: Hyperaccumulator plant species growing on metal-rich soils can accumulate high quantity of metals and metalloids in aerial tissues, and several proteomic studies on the molecular mechanisms at the basis of metals resistance and hyperaccumulation have…
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Keywords:
analysis halleri;
halleri;
caerulescens hyperaccumulators;
halleri caerulescens ... See more keywords