Immunocapture sample clean-up in determination of low abundant protein biomarkers – a feasibility study of peptide capture by anti-protein antibodies
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DOI: 10.1039/c9ra05071j
Abstract: Targeted protein biomarker determination by immunocapture LC-MS/MS: comparison of peptide and protein capture using anti-protein antibodies. read more here.
Keywords: protein; anti protein; determination; protein antibodies ... See more keywords
Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology
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DOI: 10.1111/imr.12829
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly expanded our understanding of the disease. The best‐known autoantibodies… read more here.
Keywords: protein antibodies; autoantibodies cells; disease; autoreactive cells ... See more keywords
Presence of anticitrullinated protein antibodies in a large population-based cohort from the Netherlands
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DOI: 10.1136/annrheumdis-2016-209991
Abstract: Objectives To determine the prevalence of anticitrullinated protein antibodies (ACPAs) and their association with known rheumatoid arthritis (RA) risk factors in the general population. Methods Lifelines is a multidisciplinary prospective population-based cohort study in the… read more here.
Keywords: based cohort; population based; protein antibodies; acpa positive ... See more keywords
P018 Anti-carbamylated protein antibodies as a clinical response predictor in rheumatoid arthritis patients treated with abatacept
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DOI: 10.1136/annrheumdis-2018-ewrr2019.13
Abstract: Career situation of first and presenting author Student for a master or a PhD. Introduction The presence of anti-carbamylated protein antibodies (anti-CarP) has been detected in rheumatoid arthritis (RA).1 Anti-CarP autoAbs target proteins that are… read more here.
Keywords: anti ccp; protein antibodies; carp; clinical response ... See more keywords
Divergent and dominant anti-inflammatory effects of patient-derived anticitrullinated protein antibodies (ACPA) in arthritis development
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DOI: 10.1136/ard-2022-223417
Abstract: About two thirds of rheumatoid arthritis (RA) patients develop anti-citrullinated protein antibodies (ACPA), which are a characteristic of the disease and sparsely observed in other clinical settings or in the healthy population. ACPA are used… read more here.
Keywords: disease; development; arthritis; protein antibodies ... See more keywords
Current view on the pathogenic role of anti-citrullinated protein antibodies in rheumatoid arthritis
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DOI: 10.1136/rmdopen-2020-001228
Abstract: Epidemiological findings suggest a potential role for anti-citrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) pathogenesis. ACPA-positive RA is associated with unique genetical and environmental risk factors, in contrast to seronegative RA. ACPA-positive healthy individuals… read more here.
Keywords: protein antibodies; anti citrullinated; citrullinated protein; role anti ... See more keywords
The Prevalence of Anticitrullinated Protein Antibodies in Older Poles—Results from a Population-Based PolSenior Study
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DOI: 10.3390/ijerph192114216
Abstract: Little is known about the occurrence of antibodies in older subjects. We analyzed the prevalence of anticitrullinated protein antibodies (anti-CCP) in a representative cohort of Polish older adults, participants of PolSenior substudy. Randomly selected 1537… read more here.
Keywords: anticitrullinated protein; prevalence anticitrullinated; anti ccp; seropositivity ... See more keywords