Detection of anti-citrullinated protein antibody (ACPA) in saliva for rheumatoid arthritis using DBA mice infected with Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.104510
Abstract: OBJECTIVE The anti-citrullinated protein antibody (ACPA), an autoantibody of rheumatoid arthritis (RA), is very specific in the diagnosis of RA and has been detected in early cases and several years before the onset of the… read more here.
Keywords: arthritis; saliva; anti citrullinated; citrullinated protein ... See more keywords
Recent advances in proteolytic stability for peptide, protein, and antibody drug discovery.
Sign Up to like & getrecommendations! Published in 2021 at "Expert opinion on drug discovery"
DOI: 10.1080/17460441.2021.1942837
Abstract: Introduction: To discover and develop a peptide, protein, or antibody into a drug requires overcoming multiple challenges to obtain desired properties. Proteolytic stability is one of the challenges and deserves a focused investigation.Areas covered: This… read more here.
Keywords: stability; peptide protein; proteolytic stability; drug ... See more keywords
Anti-citrullinated protein antibody profiles predict changes in disease activity in patients with rheumatoid arthritis initiating biologics.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead260
Abstract: OBJECTIVES To determine whether an expanded antigen-specific anti-citrullinated protein antibody (ACPA) profile predicts changes in disease activity in patients with rheumatoid arthritis (RA) initiating biologics. METHODS The study included participants from a prospective, non-randomized, observational… read more here.
Keywords: citrullinated protein; protein antibody; anti citrullinated; treatment ... See more keywords
SARS-CoV-2 Infection-Blocking Immunity Post Natural Infection: The Role of Vitamin D
Sign Up to like & getrecommendations! Published in 2023 at "Vaccines"
DOI: 10.3390/vaccines11020475
Abstract: Objective and Aim: The extent of the protection against SARS-CoV-2 conferred by natural infection is unclear. Vitamin D may have a role in the interplay between SARS-CoV-2 infection and the evolving acquired immunity against it.… read more here.
Keywords: infection; anti spike; spike protein; protein antibody ... See more keywords