Multiplex screening of 275 plasma protein biomarkers to identify a signature for early detection of colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12591
Abstract: Blood‐based protein biomarkers may be an attractive option for early detection of colorectal cancer (CRC). Here, we used a two‐stage design to measure 275 protein markers by proximity extension assay (PEA), first in plasma samples… read more here.
Keywords: protein; early detection; detection colorectal; crc ... See more keywords
Highly Sensitive Detection of Protein Biomarkers with Organic Electrochemical Transistors.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201703787
Abstract: The analysis of protein biomarkers is of great importance in the diagnosis of diseases. Although many convenient and low-cost electrochemical approaches have been extensively investigated, they are not sensitive enough in the detection of protein… read more here.
Keywords: protein; organic electrochemical; electrochemical transistors; protein biomarkers ... See more keywords
Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia Open"
DOI: 10.1002/epi4.12738
Abstract: We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recovery (neuroscores), considering the effect of levetiracetam,… read more here.
Keywords: plasma protein; protein biomarkers; brain; early preclinical ... See more keywords
Plasma protein biomarkers for early detection of pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Cancer"
DOI: 10.1002/ijc.33464
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, mainly due to late diagnosis at advanced tumor stages. In this study, we aimed to identify plasma protein biomarkers for early detection of PDAC. Totally, 135 PDAC… read more here.
Keywords: protein; plasma; pdac; early detection ... See more keywords
Guidelines for CSF Processing and Biobanking: Impact on the Identification and Development of Optimal CSF Protein Biomarkers.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9706-0_2
Abstract: The field of neurological diseases strongly needs biomarkers for early diagnosis and optimal stratification of patients in clinical trials or to monitor disease progression. Cerebrospinal fluid (CSF) is one of the main sources for the… read more here.
Keywords: protein; guidelines csf; csf; csf processing ... See more keywords
Simultaneous detection and quantification of DNA and protein biomarkers in spectrum of cardiovascular diseases in a microfluidic microbead chip
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02199-x
Abstract: The rapid and simultaneous detection of DNA and protein biomarkers is necessary to detect the outbreak of a disease or to monitor a disease. For example, cardiovascular diseases are a major cause of adult mortality… read more here.
Keywords: detection; dna; dna protein; simultaneous detection ... See more keywords
Temporal Profile and Severity Correlation of a Panel of Rat Spinal Cord Injury Protein Biomarkers
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0424-7
Abstract: In the USA, there are approximately 12,000 new cases of spinal cord injury (SCI) each year and some 1.2 million people living with paralysis due to SCI. Seven percent of them are paralyzed due to… read more here.
Keywords: protein; marker; injury; protein biomarkers ... See more keywords
Analytical validation of protein biomarkers for risk of spontaneous preterm birth
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Mass Spectrometry"
DOI: 10.1016/j.clinms.2017.06.002
Abstract: Abstract Presented are the validation results of a second-generation assay for determining the relative abundances of two protein biomarkers found in maternal serum that predict an individual’s risk of spontaneous preterm birth. The sample preparation… read more here.
Keywords: validation; preterm birth; spontaneous preterm; risk spontaneous ... See more keywords
Photoelectrochemical bioanalysis of protein biomarkers
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Electrochemistry"
DOI: 10.1016/j.coelec.2018.05.008
Abstract: Photoelectrochemical (PEC) bioanalysis represents a unique and dynamically developing methodology that offers an elegant route for sensitive biomolecular detection. Protein biomarkers, generally refers to biomolecules whose presence or level of expression are indicative of the… read more here.
Keywords: photoelectrochemical bioanalysis; bioanalysis; bioanalysis protein; pec ... See more keywords
Protein biomarkers associated with pain mechanisms in osteoarthritis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2018.04.030
Abstract: Osteoarthritis (OA) is the most common arthritic disease in the world, leading to debilitating pain and destruction of joint tissues. While pain is the hallmark symptom of osteoarthritis, clear associations between pain and disease processes… read more here.
Keywords: associated pain; osteoarthritis; pain; biomarkers associated ... See more keywords
The study of protein biomarkers to understand the biochemical processes underlying beef color development in young bulls.
Sign Up to like & getrecommendations! Published in 2017 at "Meat science"
DOI: 10.1016/j.meatsci.2017.07.014
Abstract: This study investigates relationships between 21 biomarkers and meat color traits of Longissimus thoracis muscles of young Aberdeen Angus and Limousin bulls. The relationships found allowed to propose metabolic processes underlying meat color. The color… read more here.
Keywords: color; beef color; study protein; processes underlying ... See more keywords