Dissecting the general mechanisms of protein cage self‐assembly by coarse‐grained simulations
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4552
Abstract: The development of artificial protein cages has recently gained massive attention due to their promising application prospect as novel delivery vehicles for therapeutics. These nanoparticles are formed through a process called self‐assembly, in which individual… read more here.
Keywords: self assembly; protein cage; general mechanisms; self ... See more keywords
Highly ordered protein cage assemblies: A toolkit for new materials.
Sign Up to like & getrecommendations! Published in 2019 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1578
Abstract: Protein capsids are specialized and versatile natural macromolecules with exceptional properties. Their homogenous, spherical, rod-like or toroidal geometry, and spatially directed functionalities make them intriguing building blocks for self-assembled nanostructures. High degrees of functionality and… read more here.
Keywords: assemblies toolkit; cage assemblies; ordered protein; protein cage ... See more keywords
Protein Cage Nanoparticles as Delivery Nanoplatforms.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0445-3_2
Abstract: Protein cage nanoparticles are made of biomaterials, proteins, and have well-defined cage-like architectures designed and built by nature. They are composed of multiple copies of one or a small number of chemically identical subunits having… read more here.
Keywords: cage; protein cage; delivery nanoplatforms; cage nanoparticles ... See more keywords
Structure of a robust bacterial protein cage and its application as a versatile biocatalytic platform through enzyme encapsulation.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.059
Abstract: Using a newly discovered encapsulin from Mycolicibacterium hassiacum, several biocatalysts were packaged in this robust protein cage. The encapsulin was found to be easy to produce as recombinant protein. Elucidation of its crystal structure revealed… read more here.
Keywords: protein; structure robust; protein cage; encapsulation ... See more keywords
Artificial Protein Cage with Unusual Geometry and Regularly Embedded Gold Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Nano Letters"
DOI: 10.1021/acs.nanolett.1c04222
Abstract: Artificial protein cages have great potential in a number of areas including cargo capture and delivery and as artificial vaccines. Here, we investigate an artificial protein cage whose assembly is triggered by gold nanoparticles. Using… read more here.
Keywords: gold nanoparticles; cage; protein cage; geometry ... See more keywords
Biocatalytic atom transfer radical polymerization in a protein cage nanoreactor
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c6py02155g
Abstract: Incorporation of the ATRP-catalyzing enzyme horseradish peroxidase (HRP) into the cavities of the group II chaperonin thermosome is demonstrated. The resulting nanoreactor was used to polymerize an acrylate under ARGET ATRP conditions. The confined space… read more here.
Keywords: nanoreactor; atom transfer; transfer radical; protein cage ... See more keywords
Chemically induced protein cage assembly with programmable opening and cargo release
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abj9424
Abstract: An artificial protein cage can be programmed to disassemble on demand. read more here.
Keywords: induced protein; chemically induced; cage; protein cage ... See more keywords
Assembly of Protein Cages for Drug Delivery
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122609
Abstract: Nanoparticles (NPs) have been widely used as target delivery vehicles for therapeutic goods; however, compared with inorganic and organic nanomaterials, protein nanomaterials have better biocompatibility and can self-assemble into highly ordered cage-like structures, which are… read more here.
Keywords: protein cage; drug; delivery; drug delivery ... See more keywords