Complex Nature of Protein Carbonylation Specificity After Metal-Catalyzed Oxidation
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Research"
DOI: 10.1007/s11095-017-2103-9
Abstract: ABSTRACTPurposeProtein carbonylation is an irreversible modification of Lys, Arg, Thr and Pro amino acids under conditions of oxidative stress. Previous studies have reported specific carbonylated residues in purified recombinant albumins, albeit with a lack of… read more here.
Keywords: carbonylation; site; protein carbonylation; metal catalyzed ... See more keywords
Role of Glutathione-S-Transferase Polymorphism on Arsenic-Induced Protein Carbonylation and Urinary Deoxy Guanosine Status
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DOI: 10.1007/s12403-019-00319-7
Abstract: Oxidative stress is significantly associated with chronic arsenic exposure in persons exposed to moderate-to-high level of environmental arsenic. However, the response varies widely among persons within similar exposure level. To study whether Glutathione-S-Transferase (GST) gene… read more here.
Keywords: status; arsenic; protein carbonylation; exposure ... See more keywords
Protein carbonylation sites in bovine raw milk and processed milk products.
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DOI: 10.1016/j.foodchem.2017.02.102
Abstract: During thermal treatment of milk, proteins are oxidized, which may reduce the nutritional value of milk, abolish protein functions supporting human health, especially important for newborns, and yield potentially harmful products. The side chains of… read more here.
Keywords: milk; carbonylation sites; sites bovine; protein carbonylation ... See more keywords
Centenarian offspring: A model for understanding healthy aging
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DOI: 10.1016/j.freeradbiomed.2018.04.257
Abstract: Centenarians exhibit extreme longevity showing a compression of morbidity. We showed previously that microRNA expression profiles and plasma protein carbonylation in centenarians and young people are similar, whereas they are very different from that found… read more here.
Keywords: protein carbonylation; centenarian offspring; healthy aging; microrna expression ... See more keywords
Sperm protein carbonylation
Sign Up to like & getrecommendations! Published in 2019 at "Andrologia"
DOI: 10.1111/and.13233
Abstract: The cryopreservation of sperm is a well established technique that plays an essential role in dissemination of elite germplasm of livestock. Despite having numerous advantages, the cryopreservation induces certain stresses on sperm including structural and… read more here.
Keywords: carbonylation; sperm protein; protein carbonylation;
Investigation and identification of protein carbonylation sites based on position-specific amino acid composition and physicochemical features
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DOI: 10.1186/s12859-017-1472-8
Abstract: BackgroundProtein carbonylation, an irreversible and non-enzymatic post-translational modification (PTM), is often used as a marker of oxidative stress. When reactive oxygen species (ROS) oxidized the amino acid side chains, carbonyl (CO) groups are produced especially… read more here.
Keywords: carbonylation sites; amino acid; protein carbonylation; carbonylation ... See more keywords
Reactive oxygen species-induced protein carbonylation promotes deterioration of physiological activity of wheat seeds
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DOI: 10.1371/journal.pone.0263553
Abstract: During the seed aging process, reactive oxygen species (ROS) can induce the carbonylation of proteins, which changes their functional properties and affects seed vigor. However, the impact and regulatory mechanisms of protein carbonylation on wheat… read more here.
Keywords: wheat; seed; seed vigor; protein carbonylation ... See more keywords
Increases in serum carbonylated protein levels of dogs with hypercortisolism.
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DOI: 10.1507/endocrj.ej22-0075
Abstract: Protein carbonylation is an irreversible and degenerative modification that can be used to evaluate oxidative stress caused by glucocorticoids. In this study, we focused on protein carbonylation in dogs with hypercortisolism (HC). Sera samples were… read more here.
Keywords: carbonylation; protein carbonylation; dogs hypercortisolism; carbonylated protein ... See more keywords
Proteome-wide analysis of hydrogen peroxide-induced protein carbonylation in Arabidopsis thaliana
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DOI: 10.3389/fpls.2022.1049681
Abstract: Introduction Protein carbonylation is a non-enzymatic and irreversible post-translational modification that occurs naturally in living organisms under the direct or indirect effect of reactive oxygen species (ROS). In animals, signaling pathways involving numerous carbonylated proteins… read more here.
Keywords: hydrogen peroxide; carbonylation; protein carbonylation; h2o2 ... See more keywords