A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo.
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DOI: 10.1021/jacs.8b04001
Abstract: Laboratory time scale evolution in vivo relies on the generation of large, mutationally diverse gene libraries to rapidly explore biomolecule sequence landscapes. Traditional global mutagenesis methods are problematic because they introduce many off-target mutations that… read more here.
Keywords: dna regions; dna; defined dna; protein chimera ... See more keywords