Evaluation of fusion protein cleavage site sequences of Newcastle disease virus in genotype matched vaccines
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DOI: 10.1371/journal.pone.0173965
Abstract: Newcastle disease virus (NDV) causes a devastating poultry disease worldwide. Frequent outbreaks of NDV in chickens vaccinated with conventional live vaccines suggest a need to develop new vaccines that are genetically matched against circulating NDV… read more here.
Keywords: protein cleavage; virus; cleavage site; cleavage ... See more keywords
In Silico Screening and Testing of FDA-Approved Small Molecules to Block SARS-CoV-2 Entry to the Host Cell by Inhibiting Spike Protein Cleavage
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DOI: 10.3390/v14061129
Abstract: The COVID-19 pandemic began in 2019, but it is still active. The development of an effective vaccine reduced the number of deaths; however, a treatment is still needed. Here, we aimed to inhibit viral entry… read more here.
Keywords: protein; host cell; protein cleavage; entry host ... See more keywords