A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane
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DOI: 10.1073/pnas.2122531119
Abstract: Significance Two-dimensional condensates of proteins on the membrane surface, driven by tyrosine phosphorylation, are beginning to emerge as important players in signal transduction. This work describes discovery of a protein condensation phase transition of EGFR… read more here.
Keywords: grb2; protein condensate; component protein; two component ... See more keywords