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Published in 2020 at "Protein Science"
DOI: 10.1002/pro.3996
Abstract: Structures of proteins and protein–protein complexes are determined by the same physical principles and thus share a number of similarities. At the same time, there could be differences because in order to function, proteins interact…
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Keywords:
protein;
structural motifs;
protein interfaces;
protein protein ... See more keywords
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Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00497
Abstract: Human UDP-glucose dehydrogenase (hUGDH) oxidizes UDP-glucose to UDP-glucuronic acid, an essential substrate in the phase II metabolism of drugs. The activity of hUGDH is regulated by the conformation of a buried allosteric switch (T131 loop/α6…
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Keywords:
state;
udp glucose;
hysteresis;
protein core ... See more keywords
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Published in 2017 at "ACS Macro Letters"
DOI: 10.1021/acsmacrolett.7b00049
Abstract: Nanoengineered vaccine platforms can be modeled after viruses and other pathogens with highly organized and repetitive structures that trigger the host immune system. Here we demonstrated a pyridine-grafted poly(e-caprolactone)-based polymer–protein core–shell nanoparticles (PPCS-NPs) platform can…
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Keywords:
protein core;
core shell;
polymer protein;
shell nanoparticles ... See more keywords