The Protein Corona Conundrum: Exploring the Advantages and Drawbacks of its Presence around Amphiphilic Nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.0c00564
Abstract: The success of targeted drug delivery systems still requires a detailed understanding about the biological consequences of self-developed biomolecular coronas around them, since this is the surface that interacts with living cells. Herein, we report… read more here.
Keywords: corona conundrum; presence; chemistry; protein coronas ... See more keywords
Nanoparticle Association with Brain Cells Is Augmented by Protein Coronas Formed in Cerebrospinal Fluid.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.4c01179
Abstract: Neuronanomedicine harnesses nanoparticle technology for the treatment of neurological disorders. An unavoidable consequence of nanoparticle delivery to biological systems is the formation of a protein corona on the nanoparticle surface. Despite the well-established influence of… read more here.
Keywords: protein corona; protein coronas; nanoparticle; brain ... See more keywords
A reflection on ‘Protein coronas suppress the hemolytic activity of hydrophilic and hydrophobic nanoparticles’
Sign Up to like & getrecommendations! Published in 2024 at "Materials Horizons"
DOI: 10.1039/d4mh90011a
Abstract: Rotello et al. reflect on their first Materials Horizons paper (Mater. Horiz., 2014, https://doi.org/10.1039/C3MH00075C) published in the inaugural issue of the journal, and discuss how their work may have influenced the research field over the… read more here.
Keywords: protein coronas; coronas suppress; hemolytic activity; reflection protein ... See more keywords
Coarse-grained simulations of lysozyme-silica-nanoparticle corona.
Sign Up to like & getrecommendations! Published in 2023 at "Biointerphases"
DOI: 10.1116/6.0002736
Abstract: Protein coronas, formed by proteins and nanomaterials, have various applications in the biomedical field. Here, large-scale simulations of protein coronas have been carried out by an efficient mesoscopic coarse-grained method with the BMW-MARTINI force field.… read more here.
Keywords: grained simulations; protein coronas; coarse; simulations lysozyme ... See more keywords
Evaluating the In Situ Effects of Whole Protein Coronas on the Biosensing of Antibody-Immobilized Nanoparticles Using Two-Color Fluorescence Nanoparticle Tracking Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Nanomaterials"
DOI: 10.3390/nano15030220
Abstract: The formation of protein coronas around engineered nanoparticles (ENPs) in biological environments is critical in nanomedicine, as these coronas significantly influence the biological behavior of ENPs. Despite extensive research on protein coronas, understanding the in… read more here.
Keywords: protein coronas; effects whole; protein; anti igg ... See more keywords
The Influence of Preforming Protein Coronas on the Performance of Dengue NS1 Immunoassays
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14112439
Abstract: The effect of preformed protein coronas on immunoassays for Dengue nonstructural protein 1 (NS1) immunoassays was investigated. The composition of the protein corona that forms around nanoparticle–antibody conjugates in human serum was characterized, and selected… read more here.
Keywords: influence preforming; protein coronas; ns1; ns1 immunoassays ... See more keywords