Relative contributions of endogenous and exogenous formaldehyde to formation of deoxyguanosine monoadducts and DNA-protein crosslink adducts of DNA in rat nasal mucosa
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DOI: 10.1093/toxsci/kfac119
Abstract: Abstract Understanding the dose-response for formaldehyde-induced nasal cancer in rats is complicated by (1) the uneven distribution of inhaled formaldehyde across the interior surface of the nasal cavity and, (2) the presence of endogenous formaldehyde… read more here.
Keywords: exogenous formaldehyde; dna protein; formaldehyde; formation ... See more keywords
Wss1 homolog from Candida albicans and its role in DNA–protein crosslink tolerance
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DOI: 10.1111/mmi.14518
Abstract: Candida albicans is an opportunistic yeast that can cause life‐threatening systemic infection in immunocompromised individuals. During infections, C. albicans has to cope with genotoxic stresses generated by the host immune system. DNA–protein crosslink (DPC), the… read more here.
Keywords: dna; tolerance; dna protein; protein crosslink ... See more keywords