Proximity-enhanced protein crosslinking through an alkene-tetrazine reaction.
Sign Up to like & getrecommendations! Published in 2023 at "Bioorganic chemistry"
DOI: 10.2139/ssrn.4255676
Abstract: The inverse electron demand Diels-Alder (iEDDA) reaction between a tetrazine and a strained alkene has been widely explored as useful bioorthogonal chemistry for selective labeling of biomolecules. In this work, we exploit the slow reaction… read more here.
Keywords: protein crosslinking; reaction; chemistry; enhanced protein ... See more keywords