Membrane Shape Remodeling by Protein Crowding.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.04.029
Abstract: The steric repulsion between proteins on biological membranes is one of the most generic mechanisms that cause membrane shape changes. We present a minimal model where a spontaneous curvature is induced by asymmetric protein crowding.… read more here.
Keywords: protein crowding; shape remodeling; membrane shape;
In vitro studies of DNA condensation by bridging protein in a crowding environment.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.079
Abstract: The macromolecules of the bacterial cell occupy 20-40% of the total cytosol volume, and crowded environments have long been known to compact and stabilize DNA. Nevertheless, investigations on DNA-protein binding are generally performed in the… read more here.
Keywords: condensation; protein crowding; vitro studies; dna condensation ... See more keywords
Protein Crowding and Cholesterol Increase Cell Membrane Viscosity in a Temperature Dependent Manner
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Chemical Theory and Computation"
DOI: 10.1021/acs.jctc.3c00060
Abstract: Shear viscosity of lipid membranes dictates how fast lipids, proteins, and other membrane constituents travel along the membrane and rotate around their principal axis, thus governing the rates of diffusion-limited reactions taking place at membranes.… read more here.
Keywords: viscosity; crowding cholesterol; protein crowding; membrane viscosity ... See more keywords
Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-16865-6
Abstract: Cell membranes are crowded and complex environments. To investigate the effect of protein-lipid interactions on dynamic organization in mammalian cell membranes, we have performed coarse-grained molecular dynamics simulations containing >100 copies of an inwardly rectifying… read more here.
Keywords: ion channels; protein crowding; cell membranes; dynamic organization ... See more keywords
Strength in numbers: effect of protein crowding on the shape of cell membranes
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20210883
Abstract: Continuous reshaping of the plasma membrane into pleomorphic shapes is critical for a plethora of cellular functions. How the cell carries out this enigmatic control of membrane remodeling has remained an active research field for… read more here.
Keywords: cell; membrane; effect protein; protein crowding ... See more keywords