Simple and Efficient Targeted Intracellular Protein Delivery with SelfâAssembled Nanovehicles for Effective Cancer Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201906187
Abstract: Protein therapy offers promising prospects for the treatment of various important diseases, thus it is highly desirable to develop a robust carrier that can deliver active proteins into cells. The development of a novel protein… read more here.
Keywords: protein delivery; cdeh nanovehicles; self; intracellular protein ... See more keywords
Dynamic Polymer Amphiphiles for Efficient Intracellular and In Vivo Protein Delivery.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202104355
Abstract: Intracellular delivery of proteins is receiving considerable attention in biotherapeutics for various diseases by replacing dysfunctional proteins. Successful intracellular protein delivery highly relies on the development of efficient and safe polymeric carriers, which remains a… read more here.
Keywords: protein delivery; delivery; efficient intracellular; dynamic polymer ... See more keywords
Cytosolic protein delivery using ultrasound-guided vaporization of perfluorocarbon nano-droplets.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology journal"
DOI: 10.1002/biot.202300018
Abstract: Ultrasound-guided protein delivery is promising for site-specific control of cellular functions in the deep interior of the body in a noninvasive manner. Herein, we propose a method for cytosolic protein delivery based on ultrasound-guided intracellular… read more here.
Keywords: nano droplets; protein delivery; cytosolic protein; ultrasound guided ... See more keywords
Polymeric Lids for Microcontainers for Oral Protein Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201900004
Abstract: Oral delivery of proteins and peptides is one of the main challenges in pharmaceutical drug development. Microdevices have the possibility to protect the therapeutics until release is desired, avoiding losses by degradation. One type of… read more here.
Keywords: protein; protein delivery; polymeric lids; delivery ... See more keywords
Protease-degradable microgels for protein delivery for vascularization.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.10.044
Abstract: Degradable hydrogels to deliver bioactive proteins represent an emerging platform for promoting tissue repair and vascularization in various applications. However, implanting these biomaterials requires invasive surgery, which is associated with complications such as inflammation, scarring,… read more here.
Keywords: microgels protein; protein delivery; vascularization; protease degradable ... See more keywords
Fibroin particle-supported cationic lipid layers for highly efficient intracellular protein delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.01.019
Abstract: Directly delivering therapeutic proteins into cells has promise as an intervention without side effects for protein deficiencies caused by genetic defects. However, as negatively charged macromolecules, proteins require carriers for achieving cellular uptake and maintaining… read more here.
Keywords: protein; cationic lipid; protein delivery; intracellular protein ... See more keywords
Zwitterionic Janus Dendrimer with distinct functional disparity for enhanced protein delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119233
Abstract: The development of a facile protein delivery vehicle is challenging and remains an unmet demand for clinical applications. The well-defined structure and functionality of a nanocarrier are highly desirable for the reproducibility and regulatory compliance.… read more here.
Keywords: protein; protein delivery; janus dendrimer;
Orodispersible films based on blends of trehalose and pullulan for protein delivery
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.09.016
Abstract: &NA; During the last decades the number of therapeutic proteins increased tremendously on the pharmaceutical market. However, due to their often poor stability and limitations of the administration route, the application of therapeutic proteins is… read more here.
Keywords: protein; protein delivery; trehalose pullulan; orodispersible films ... See more keywords
Controlled release strategy designed for intravitreal protein delivery to the retina
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.11.012
Abstract: &NA; Therapeutic protein delivery directly to the eye is a promising strategy to treat retinal degeneration; yet, the high risks of local drug overdose and cataracts associated with bolus injection have limited progress, requiring the… read more here.
Keywords: protein; protein delivery; intravitreal protein; delivery ... See more keywords
Affinity Hydrogels for Protein Delivery.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2021.01.005
Abstract: Proteins have been studied as therapeutic agents for treatment of various human diseases. However, the delivery of protein drugs into the body is challenging. In this review, we summarize and highlight progress in developing affinity… read more here.
Keywords: affinity hydrogels; protein delivery; release proteins; affinity ... See more keywords
Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery.
Sign Up to like & getrecommendations! Published in 2020 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.0c00903
Abstract: Tannic acid (TA) can form stable complexes with proteins, attracting significant attention as protein delivery systems. However, its systemic application has been limited due to nonspecific interaction. Here, we report a simple technique to prepare… read more here.
Keywords: acid; protein delivery; self assembly;