Functional organization of protein determinants of meiotic DNA break hotspots
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DOI: 10.1038/s41598-017-00742-3
Abstract: During Schizosaccharomyces pombe meiotic prophase, homologous chromosomes are co-aligned by linear elements (LinEs) analogous to the axial elements of the synaptonemal complex (SC) in other organisms. LinE proteins also promote the formation of meiotic DNA… read more here.
Keywords: meiotic dna; protein determinants; line proteins; formation ... See more keywords
Variable G protein determinants of GPCR coupling selectivity
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1905993116
Abstract: Significance G protein-coupled receptors (GPCRs) regulate a wide variety of important cellular processes and are targeted by a large fraction of approved drugs. GPCRs signal by activating heterotrimeric G proteins and must couple to a… read more here.
Keywords: protein; terminus; coupling selectivity; coupled receptors ... See more keywords