Gene silencing of extracellular matrix protein 1 (ECM1) results in phenotypic alterations of dermal fibroblasts reminiscent of clinical features of lichen sclerosus.
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DOI: 10.1016/j.jdermsci.2020.06.010
Abstract: BACKGROUND Lichen sclerosus (LS) is an acquired inflammatory mucocutaneous disease affecting the anogenital area, characterized histologically by hyalinosis and thickened vessel walls in the dermis. The presence of serum autoantibodies against extracellular matrix protein 1… read more here.
Keywords: matrix protein; extracellular matrix; matrix; lichen sclerosus ... See more keywords