G protein αq exerts expression level-dependent distinct signaling paradigms.
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DOI: 10.1016/j.cellsig.2019.02.006
Abstract: G protein αq-coupled receptors (Gq-GPCRs) primarily signal through GαqGTP mediated phospholipase Cβ (PLCβ) stimulation and the subsequent hydrolysis of phosphatidylinositol 4, 5 bisphosphate (PIP2). Though Gq-heterotrimer activation results in both GαqGTP and Gβγ, unlike Gi/o-receptors,… read more here.
Keywords: exerts expression; protein exerts; distinct signaling; coupled receptors ... See more keywords