Radioligands Targeting Fibroblast Activation Protein (FAP)
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DOI: 10.3390/cancers13225744
Abstract: Simple Summary FAP-targeted radiotracers, recently introduced in cancer treatment, accumulate in Cancer-Associated Fibroblasts (CAFs). CAFs are present in tumor lesions but do not correspond to genuine cancer cells, although they behave in an abnormal and… read more here.
Keywords: medicine; nuclear medicine; fap targeted; fap ... See more keywords
Design, Synthesis and Preclinical Assessment of 99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging
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DOI: 10.3390/molecules27010264
Abstract: Fibroblast activation protein (FAP) is expressed in the microenvironment of most human epithelial tumors. 68Ga-labeled FAP inhibitors based on the cyanopyrrolidine structure (FAPI) are currently used for the detection of the tumor microenvironment by PET… read more here.
Keywords: activation protein; fibroblast activation; ifap; protein fap ... See more keywords