Articles with "protein fold" as a keyword



A Thermostable Heme Protein Fold Adapted for Stereoselective C−H Bond Hydroxylation Using Peroxygenase Activity

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Published in 2024 at "ChemBioChem"

DOI: 10.1002/cbic.202400737

Abstract: Thermostable protein folds of natural and synthetic origin are highly sought‐after templates for biocatalyst generation due to their enhanced stability to elevated temperatures which overcomes one of the major limitations of applying enzymes for synthesis.… read more here.

Keywords: protein fold; protein; stereoselective bond; heme ... See more keywords

Differential proteomic response of Agaricus bisporus and Trichoderma aggressivum f. europaeum to Bacillus velezensis supernatant

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Published in 2021 at "European Journal of Plant Pathology"

DOI: 10.1007/s10658-021-02252-5

Abstract: Trichoderma aggressivum, a mycopathogen causing green mould disease, is a major problem in Agaricus bisporus cultivation due to crop loss, and resistance to chemical fungicides. There is an urgent need for novel biological ways to… read more here.

Keywords: aggressivum; proteins fold; protein fold; velezensis ... See more keywords

Extracting features from protein sequences to improve deep extreme learning machine for protein fold recognition.

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Published in 2017 at "Journal of theoretical biology"

DOI: 10.1016/j.jtbi.2017.03.023

Abstract: Protein fold recognition is an important problem in bioinformatics to predict three-dimensional structure of a protein. One of the most challenging tasks in protein fold recognition problem is the extraction of efficient features from the… read more here.

Keywords: features protein; protein fold; protein sequences; fold recognition ... See more keywords

Learning Protein Embedding to Improve Protein Fold Recognition Using Deep Metric Learning

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Published in 2022 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.2c00959

Abstract: Protein fold recognition refers to predicting the most likely fold type of the query protein and is a critical step of protein structure and function prediction. With the popularity of deep learning in bioinformatics, protein… read more here.

Keywords: fold recognition; improve protein; protein fold; deep metric ... See more keywords
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A novel fusion based on the evolutionary features for protein fold recognition using support vector machines

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-71172-x

Abstract: Protein fold recognition plays a crucial role in discovering three-dimensional structure of proteins and protein functions. Several approaches have been employed for the prediction of protein folds. Some of these approaches are based on extracting… read more here.

Keywords: information; support vector; features protein; protein fold ... See more keywords

Severe deviation in protein fold prediction by advanced AI: a case study

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-025-89516-w

Abstract: Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino acid sequences.… read more here.

Keywords: protein fold; structure; deviation protein; prediction ... See more keywords

Protein fold recognition based on multi-view modeling

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Published in 2019 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btz040

Abstract: Motivation Protein fold recognition has attracted increasing attention because it is critical for studies of the 3D structures of proteins and drug design. Researchers have been extensively studying this important task, and several features with… read more here.

Keywords: fold fold; protein fold; recognition; fold recognition ... See more keywords

An Effective Framework for Protein Fold Prediction through the Fusion of Evolutionary Information and Attention Mechanism with Deep Neural Networks.

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Published in 2025 at "IEEE journal of biomedical and health informatics"

DOI: 10.1109/jbhi.2025.3602510

Abstract: Proteins are essential for the vital functions of living organisms, playing key roles in various cellular processes. Accurate prediction of protein structures is crucial, with an important step involving the identification of the structural fold… read more here.

Keywords: protein fold; attention; protein; prediction ... See more keywords
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Protein Fold Recognition by Combining Support Vector Machines and Pairwise Sequence Similarity Scores

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Published in 2021 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"

DOI: 10.1109/tcbb.2020.2966450

Abstract: Protein fold recognition is one of the most essential steps for protein structure prediction, aiming to classify proteins into known protein folds. There are two main computational approaches: one is the template-based method based on… read more here.

Keywords: support vector; tsvm fold; protein fold; vector machines ... See more keywords