Protein Footprinting: Auxiliary Engine to Power the Structural Biology Revolution.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.02.011
Abstract: Structural biology is entering an exciting time where many new high-resolution structures of large complexes and membrane proteins are determined regularly. These advances have been driven by over fifteen years of technology advancements; first in… read more here.
Keywords: structural biology; engine power; protein footprinting; biology ... See more keywords
Development of Spheroid-FPOP: An In-Cell Protein Footprinting Method for 3D Tumor Spheroids
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00307
Abstract: Many cancer drugs fail at treating solid epithelial tumors with hypoxia and insufficient drug penetration thought to be contributing factors to the observed chemoresistance. Owing to this, it is imperative to evaluate potential cancer drugs… read more here.
Keywords: spheroid fpop; footprinting method; protein footprinting; fpop ... See more keywords
Structural Investigation of Therapeutic Antibodies Using Hydroxyl Radical Protein Footprinting Methods
Sign Up to like & getrecommendations! Published in 2022 at "Antibodies"
DOI: 10.3390/antib11040071
Abstract: Commercial monoclonal antibodies are growing and important components of modern therapies against a multitude of human diseases. Well-known high-resolution structural methods such as protein crystallography are often used to characterize antibody structures and to determine… read more here.
Keywords: hydroxyl radical; protein footprinting; structural investigation; radical protein ... See more keywords