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DeepFunc: A Deep Learning Framework for Accurate Prediction of Protein Functions from Protein Sequences and Interactions

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1 Published in 2019 at "PROTEOMICS"

DOI: 10.1002/pmic.201900019

Abstract: Annotation of protein functions plays an important role in understanding life at the molecular level. High‐throughput sequencing produces massive numbers of raw proteins sequences and only about 1% of them have been manually annotated with… read more here.

Keywords: protein; deep learning; learning framework; functions protein ... See more keywords

Succinylation Links Metabolism to Protein Functions

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1 Published in 2019 at "Neurochemical Research"

DOI: 10.1007/s11064-019-02780-x

Abstract: Post-translational modifications (PTMs) are important regulators of protein function, and integrate metabolism with physiological and pathological processes. Phosphorylation and acetylation are particularly well studied PTMs. A relatively recently discovered novel PTM is succinylation in which… read more here.

Keywords: metabolism protein; succinylation; metabolism; succinylation links ... See more keywords

Graph2GO: a multi-modal attributed network embedding method for inferring protein functions

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1 Published in 2020 at "GigaScience"

DOI: 10.1093/gigascience/giaa081

Abstract: Abstract Background Identifying protein functions is important for many biological applications. Since experimental functional characterization of proteins is time-consuming and costly, accurate and efficient computational methods for predicting protein functions are in great demand for… read more here.

Keywords: network; graph2go multi; model; multi modal ... See more keywords

Predicting protein functions by applying predicate logic to biomedical literature

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0 Published in 2019 at "BMC Bioinformatics"

DOI: 10.1186/s12859-019-2594-y

Abstract: BackgroundA large number of computational methods have been proposed for predicting protein functions. The underlying techniques adopted by most of these methods revolve around predicting the functions of an unannotated protein p from already annotated… read more here.

Keywords: biomedical texts; ppf; explicitly mentioned; biomedical literature ... See more keywords

Transmembrane Protein 68 Functions as an MGAT and DGAT Enzyme for Triacylglycerol Biosynthesis

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2 Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24032012

Abstract: Triacylglycerol (TG) biosynthesis is an important metabolic process for intracellular storage of surplus energy, intestinal dietary fat absorption, attenuation of lipotoxicity, lipid transportation, lactation and signal transduction in mammals. Transmembrane protein 68 (TMEM68) is an… read more here.

Keywords: triacylglycerol biosynthesis; transmembrane protein; functions mgat; protein functions ... See more keywords