Non‐sedating antihistamines block G‐protein‐gated inwardly rectifying K+ channels
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DOI: 10.1111/bph.14717
Abstract: A second‐generation antihistamine, terfenadine, is known to induce arrhythmia by blocking hERG channels. In this study, we have shown that terfenadine also inhibits the activity of G‐protein‐gated inwardly rectifying K+ (GIRK) channels, which regulate the… read more here.
Keywords: protein gated; sedating antihistamines; gated inwardly; inwardly rectifying ... See more keywords