DPAGT1‐Mediated Protein N‐Glycosylation Is Indispensable for Oocyte and Follicle Development in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.202000531
Abstract: Abstract Post‐translational modification of proteins by N‐linked glycosylation is crucial for many life processes. However, the exact contribution of N‐glycosylation to mammalian female reproduction remains largely undefined. Here, DPAGT1, the enzyme that catalyzes the first… read more here.
Keywords: indispensable oocyte; protein glycosylation; dpagt1; glycosylation ... See more keywords
Advances in glycopeptide enrichment methods for the analysis of protein glycosylation over the past decade.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200292
Abstract: Advances in bioanalytical technology have accelerated the analysis of complex protein glycosylation, which is beneficial to understanding glycosylation in drug discovery and disease diagnosis. Due to its biological uniqueness in the course of disease occurrence… read more here.
Keywords: protein glycosylation; glycopeptide enrichment; enrichment methods; analysis ... See more keywords
Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-020-01715-6
Abstract: It is crucial to identify risk factors for life prognosis after hepatitis C virus (HCV) eradication among patients with or without a high risk of liver cancer or complications. This is a prospective, multicenter and… read more here.
Keywords: eradication; mac binding; hcc; protein glycosylation ... See more keywords
The role of protein glycosylation in muscle diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07334-z
Abstract: INTRODUCTION As a post-translational modification, glycosylation plays vital role in regulating the folding and function of proteins necessary for many biological processes. Unlike glycation, glycosylation is an enzymatic process; glycosyltransferases transfer sugars to proteins, forming… read more here.
Keywords: role; muscle diseases; muscle; glycosylation ... See more keywords
Protein glycosylation
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2019.01.003
Abstract: Eichler introduces the diversity of protein glycosylations and the roles of these modifications in regulating protein function. read more here.
Keywords: protein; protein glycosylation; biology;
Microbial glycoproteomics.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2017.03.005
Abstract: Mass spectrometry-based "-omics" technologies are important tools for global and detailed mapping of post-translational modifications. Protein glycosylation is an abundant and important post translational modification widespread throughout all domains of life. Characterization of glycoproteins, including… read more here.
Keywords: protein glycosylation; biology; microbial glycoproteomics;
Multiple Reaction Monitoring for the Quantitation of Serum Protein Glycosylation Profiles: Application to Ovarian Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.7b00541
Abstract: Protein glycosylation fingerprints are widely recognized as potential markers for disease states, and indeed differential glycosylation has been identified in multiple types of autoimmune diseases and several types of cancer. However, releasing the glycans leave… read more here.
Keywords: protein; protein glycosylation; multiple reaction; serum ... See more keywords
Quantification of Protein Glycosylation Using Nanopores
Sign Up to like & getrecommendations! Published in 2022 at "Nano Letters"
DOI: 10.1021/acs.nanolett.2c01338
Abstract: Although nanopores can be used for single-molecule sequencing of nucleic acids using low-cost portable devices, the characterization of proteins and their modifications has yet to be established. Here, we show that hydrophilic or glycosylated peptides… read more here.
Keywords: protein glycosylation; quantification protein; using nanopores; glycosylation using ... See more keywords
The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Psychiatry"
DOI: 10.1038/s41380-022-01490-1
Abstract: A missense mutation (A391T) in SLC39A8 is strongly associated with schizophrenia in genomic studies, though the molecular connection to the brain is unknown. Human carriers of A391T have reduced serum manganese, altered plasma glycosylation, and… read more here.
Keywords: glycosylation; schizophrenia; schizophrenia associated; protein glycosylation ... See more keywords
Crosstalk between protein N-glycosylation and lipid metabolism in Saccharomyces cerevisiae
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DOI: 10.1038/s41598-019-51054-7
Abstract: The endoplasmic reticulum (ER) is a multi functional organelle and plays a crucial role in protein folding and lipid biosynthesis. The SEC59 gene encodes dolichol kinase, required for protein glycosylation in the ER. The mutation… read more here.
Keywords: protein glycosylation; sec59; glycosylation; crosstalk protein ... See more keywords
Tankyrase-1-mediated degradation of Golgin45 regulates glycosyltransferase trafficking and protein glycosylation in Rab2-GTP-dependent manner
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DOI: 10.1038/s42003-021-02899-0
Abstract: Altered glycosylation plays an important role during development and is also a hallmark of increased tumorigenicity and metastatic potentials of several cancers. We report here that Tankyrase-1 (TNKS1) controls protein glycosylation by Poly-ADP-ribosylation (PARylation) of… read more here.
Keywords: dependent manner; rab2 gtp; glycosylation; gtp dependent ... See more keywords