Downregulation of hedgehog-interacting protein (HHIP) contributes to hexavalent chromium-induced malignant transformation of human bronchial epithelial cells.
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DOI: 10.1093/carcin/bgaa085
Abstract: Hexavalent chromium [Cr(VI)] is a potent human lung carcinogen. Multiple mechanisms have been proposed that contribute to Cr(VI)-induced lung carcinogenesis including oxidative stress, DNA damage, genomic instability, and epigenetic modulation. However, the molecular mechanisms and… read more here.
Keywords: transformed cells; hedgehog interacting; hhip; hexavalent chromium ... See more keywords