The neural ELAVL protein HuB enhances endogenous proto-oncogene activation.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.07.089
Abstract: The cytoplasmic distribution of the HuR/ELAVL1 (embryonic lethal abnormal vision 1) protein is recognized as an important prognostic factor of malignant tumors. However, the previous study suggests that exogenous over-expression of HuR is not sufficient… read more here.
Keywords: protein; hub; proto; protein hub ... See more keywords
Real-Time Measurement of a Weak Interaction of a Transcription Factor Motif with a Protein Hub at Single-Molecule Precision
Sign Up to like & getrecommendations! Published in 2024 at "ACS Nano"
DOI: 10.1021/acsnano.4c04857
Abstract: Transcription factors often interact with other protein cofactors, regulating gene expression. Direct detection of these brief events using existing technologies remains challenging due to their transient nature. In addition, intrinsically disordered domains, intranuclear location, and… read more here.
Keywords: transcription factor; protein hub; interaction; transcription ... See more keywords