Harnessing the Power of Proteolysis for Targeted Protein Inactivation.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.01.010
Abstract: Two decades into the twenty-first century, a confluence of breakthrough technologies wielded at the molecular level is presenting biologists with unique opportunities to unravel the complexities of the cellular world. CRISPR/Cas9 allows gene knock-outs, knock-ins,… read more here.
Keywords: harnessing power; protein inactivation; power proteolysis; proteolysis targeted ... See more keywords
Green monomeric photosensitizing fluorescent protein for photo-inducible protein inactivation and cell ablation
Sign Up to like & getrecommendations! Published in 2018 at "BMC Biology"
DOI: 10.1186/s12915-018-0514-7
Abstract: BackgroundPhotosensitizing fluorescent proteins, which generate reactive oxygen species (ROS) upon light irradiation, are useful for spatiotemporal protein inactivation and cell ablation. They give us clues about protein function, intracellular signaling pathways and intercellular interactions. Since… read more here.
Keywords: protein; protein inactivation; inactivation cell; inactivation ... See more keywords