Roles of Serum Amyloid A 1 Protein Isoforms in Rheumatoid Arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Engineering"
DOI: 10.1016/j.eng.2020.08.018
Abstract: Abstract Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexists with over-secretion of the serum amyloid A 1 (SAA1) protein and deposition in key internal organs. Previously, using the… read more here.
Keywords: protein; saa1 protein; rheumatoid arthritis; serum amyloid ... See more keywords
Proteogenomics Integrating Novel Junction Peptide Identification Strategy Discovers Three Novel Protein Isoforms of Human NHSL1 and EEF1B2.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00373
Abstract: In eukaryotes, alternative pre-mRNA splicing allows a single gene to encode different protein isoforms that function in many biological processes, and they are used as biomarkers or therapeutic targets for diseases. Although protein isoforms in… read more here.
Keywords: protein; novel protein; novel junction; isoforms human ... See more keywords
Identification of Protein Isoforms Using Reference Databases Built from Long and Short Read RNA-Sequencing.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00968
Abstract: Alternative splicing can lead to distinct protein isoforms. These can have different functions in specific cells and tissues or in different developmental stages. In this study, we explored whether transcripts assembled from long read, nanopore-based,… read more here.
Keywords: rna seq; read rna; protein isoforms; identification protein ... See more keywords
Alternative 3′ UTRs direct localization of functionally diverse protein isoforms in neuronal compartments
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky1270
Abstract: The proper subcellular localization of RNAs and local translational regulation is crucial in highly compartmentalized cells, such as neurons. RNA localization is mediated by specific cis-regulatory elements usually found in mRNA 3'UTRs. Therefore, processes that… read more here.
Keywords: protein isoforms; alternative utrs; localization functionally; functionally diverse ... See more keywords
Lyssavirus P Protein Isoforms Diverge Significantly in Subcellular Interactions Underlying Mechanisms of Interferon Antagonism
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01396-22
Abstract: Lyssaviruses, including rabies virus, cause rabies, a progressive encephalomyelitis that is almost invariably fatal. There are no effective antivirals for symptomatic infection, and effective application of current vaccines is limited in areas of endemicity, such… read more here.
Keywords: lyssavirus protein; protein isoforms; host; virus ... See more keywords
DeepLPI: a multimodal deep learning method for predicting the interactions between lncRNAs and protein isoforms
Sign Up to like & getrecommendations! Published in 2021 at "BMC Bioinformatics"
DOI: 10.1186/s12859-020-03914-7
Abstract: Background Long non-coding RNAs (lncRNAs) regulate diverse biological processes via interactions with proteins. Since the experimental methods to identify these interactions are expensive and time-consuming, many computational methods have been proposed. Although these computational methods… read more here.
Keywords: protein; predicting interactions; lncrnas protein; interactions lncrnas ... See more keywords
Molecular modelling of the HCMV IL-10 protein isoforms and analysis of their interaction with the human IL-10 receptor
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277953
Abstract: The human cytomegalovirus (HCMV) UL111A gene encodes several homologs of the cellular interleukin 10 (cIL-10). Alternative splicing in the UL111A region produces two relatively well-characterized transcripts designated cmvIL-10 (isoform A) and LAcmvIL-10 (isoform B). The… read more here.
Keywords: molecular modelling; hcmv; protein isoforms; receptor ... See more keywords
Corrigendum: Identification and Characterization of Three Epithiospecifier Protein Isoforms in Brassica oleracea
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00523
Abstract: [This corrects the article on p. 1552 in vol. 10, PMID: 31921230.]. read more here.
Keywords: characterization three; three epithiospecifier; corrigendum identification; epithiospecifier protein ... See more keywords
Signification of Protein P-53 Isoforms in CLL
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DOI: 10.4172/2167-7700.1000256
Abstract: In the past few years has used the technique for analyzing deletions of genes, its rearrangements, cross-reactivity or multiplications in human genome affected of a variety genetic diseases. Was proved, the best techniques in the investigation of… read more here.
Keywords: signification protein; isoforms cll; protein isoforms; medicine ... See more keywords