Processed pseudogene confounding the identification of a putative lethal recessive deletion in the bovine 60S ribosomal protein L11 gene (uL5).
Sign Up to like & getrecommendations! Published in 2019 at "Animal genetics"
DOI: 10.1111/age.12868
Abstract: Background: In higher eukaryotes, impaired ribosome biogenesis and function can result in specific phenotypes, the so-called ribosomopathies. In humans at least six ribosomopathies have been described, i.e. Diamond–Blackfan anemia (DBA), 5q-syndrome, Shwachman–Diamond syndrome, X-linked dyskeratosis… read more here.
Keywords: 60s ribosomal; protein l11; gene ul5; 129 195 ... See more keywords
UBE2M Drives Hepatocellular Cancer Progression as a p53 Negative Regulator by Binding to MDM2 and Ribosomal Protein L11
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13194901
Abstract: Simple Summary Herein, the oncogenic role of UBE2M as an E2 NEDD8-conjugating enzyme was explored in hepatocellular carcinoma (HCC) cells, since neddylation plays a critical role in tumorigenesis. To address this issue, human tissue array… read more here.
Keywords: protein l11; ribosomal protein; mdm2 ribosomal; p53 ... See more keywords