Quantifying cooperative multisite binding in the hub protein LC8 through Bayesian inference
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DOI: 10.1101/2022.06.29.498022
Abstract: Multistep protein-protein interactions underlie most biological processes, but their characterization through methods such as isothermal titration calorimetry (ITC) is largely confined to simple models that provide little information on the intermediate, individual steps. In this… read more here.
Keywords: itc; protein lc8; hub protein; protein ... See more keywords
Systematic identification of recognition motifs for the hub protein LC8
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DOI: 10.26508/lsa.201900366
Abstract: LC8 is a eukaryotic hub protein that interacts with multifarious partners; analysis of more than 100 binding/nonbinding sequences led to an algorithm that predicts LC8 partners with 78% accuracy. Hub proteins participate in cellular regulation… read more here.
Keywords: lc8; systematic identification; protein lc8; anchor ... See more keywords