Articles with "protein mcph1" as a keyword



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Microcephaly family protein MCPH1 stabilizes RAD51 filaments

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Published in 2020 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaa636

Abstract: Abstract Microcephalin 1 (MCPH1) was identified from genetic mutations in patients with primary autosomal recessive microcephaly. In response to DNA double-strand breaks (DSBs), MCPH1 forms damage-induced foci and recruits BRCA2–RAD51 complex, a key component of… read more here.

Keywords: protein; microcephaly family; family protein; protein mcph1 ... See more keywords