Protein methylome analysis in Arabidopsis reveals regulation in RNA-related processes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2019.103601
Abstract: Protein methylation has been proposed as an important post-translational modification, which occurs predominantly on lysine and arginine residues. Recent discoveries have revealed that protein methylation is also present on non-histones besides histones, and plays critical… read more here.
Keywords: methylation sites; methylation; analysis; protein methylation ... See more keywords
Strategy Based on Deglycosylation, Multiprotease, and Hydrophilic Interaction Chromatography for Large-Scale Profiling of Protein Methylation.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b03673
Abstract: Reversible methylation of proteins regulates the majority of cellular processes, including signal transduction, mRNA splicing, transcriptional control, DNA repair, and protein translocation. A fundamental understanding of these biological processes at the molecular level requires comprehensive… read more here.
Keywords: chromatography; methylation; hydrophilic interaction; strategy ... See more keywords
Non-Histone Protein Methylation: Biological Significance and Bioengineering Potential.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical biology"
DOI: 10.1021/acschembio.0c00771
Abstract: Protein methylation is a key post-translational modification whose effects on gene expression have been intensively studied over the last two decades. Recently, renewed interest in non-histone protein methylation has gained momentum for its role in… read more here.
Keywords: protein; protein methylation; histone protein; non histone ... See more keywords
The protein methylation network in yeast: A landmark in completeness for a eukaryotic post-translational modification.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2215431120
Abstract: Defining all sites for a post-translational modification in the cell, and identifying their upstream modifying enzymes, is essential for a complete understanding of a modification's function. However, the complete mapping of a modification in the… read more here.
Keywords: methylation; network; modification; post translational ... See more keywords
Multifactorial feature extraction and site prognosis model for protein methylation data.
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elac034
Abstract: Integrated studies (multi-omics studies) comprising genetic, proteomic and epigenetic data analyses have become an emerging topic in biomedical research. Protein methylation is a posttranslational modification that plays an essential role in various cellular activities. The… read more here.
Keywords: methylation; methylation sites; protein methylation; methylation data ... See more keywords
Fast Prediction of Protein Methylation Sites Using a Sequence-Based Feature Selection Technique
Sign Up to like & getrecommendations! Published in 2019 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2017.2670558
Abstract: Protein methylation, an important post-translational modification, plays crucial roles in many cellular processes. The accurate prediction of protein methylation sites is fundamentally important for revealing the molecular mechanisms undergoing methylation. In recent years, computational prediction… read more here.
Keywords: methylation sites; protein methylation; methylation; sequence ... See more keywords
Protein Methylation in Diabetic Kidney Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.736006
Abstract: Chronic kidney disease (CKD) is defined by persistent urine aberrations, structural abnormalities, or impaired excretory renal function. Diabetes is the leading cause of CKD. Their common pathological manifestation is renal fibrosis. Approximately half of all… read more here.
Keywords: protein methylation; methylation; diabetic kidney; kidney disease ... See more keywords