Inhibitors of Protein Methyltransferases and Demethylases
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DOI: 10.1021/acs.chemrev.6b00801
Abstract: Post-translational modifications of histones by protein methyltransferases (PMTs) and histone demethylases (KDMs) play an important role in the regulation of gene expression and transcription and are implicated in cancer and many other diseases. Many of… read more here.
Keywords: inhibitors protein; methyltransferases demethylases; protein methyltransferases;
Understanding the Roles of the NSD Protein Methyltransferases in Head and Neck Squamous Cell Carcinoma
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DOI: 10.3390/genes13112013
Abstract: Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent non-skin cancer in the world. While immunotherapy has revolutionized the standard of care treatment in patients with recurrent/metastatic HNSCC, more than 70% of… read more here.
Keywords: cell carcinoma; head neck; squamous cell; protein methyltransferases ... See more keywords
Special Issue “Structure, Activity, and Function of Protein Methyltransferases”
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DOI: 10.3390/life12030405
Abstract: Post-translational modifications (PTMs) largely expand the functional diversity of the proteome [...]. read more here.
Keywords: special issue; structure activity; function protein; protein methyltransferases ... See more keywords